... after each interview. Here's what to say.
Do not agonize over the content; a thank-you note will not get you a job. Most people will have decided whether or not to offer you a job before you even leave the building, but occasionally, the lack of a thank-you note will be noticed. So, just do it, quickly, with good grammar and perfect spelling.
Thank your interviewer for spending time with you, and briefly (in three to four sentences) make the case again about why you are qualified for the job. You may want to make a specific reference to something you discussed in the interview. If there is something you think you forgot to tell about yourself, and you believe it is important, briefly mention it. And reiterate your interest in the position.
For most jobs in most industries these days, it is perfectly acceptable to send a thank-you e-mail. Make sure you get the interviewer’s business card so you have the right title and both snail and e-mail addresses. And send it quickly—at least by the following day.